DrLucindaEdwards(NiamhAlgar)isasmart,battle-hardeneddoctor,butwemeetheronanightmareshiftthatendsinthedeathofanopioidoverdosevictim,EdithOwusu.Despitethesupportofhermedicalsupervisor,DrLeoHarris,playedbyJamesPurefoy(ADiscoveryofWitches,Pennyworth,SexEducation),Edith'sgrievingfatherSirAnthonyOwusu,playedbyBrianBovell(Crime,Strike),demandsanenquiryintoLucinda'sactionsonthefatefulnight.LeadingthemedicalinvestigationareDrNormaCallahanplayedbyHelenBehan(Holding,TheVirtues)andLucinda'sformercolleague,DrGeorgeAdjei,playedbyJordanKouamé(Megalomania).WhileGeorgefeelsthiswasanunavoidabletragedy,NormaissuspiciousofLucinda'sbehaviouranddecisionsintheleaduptoEdith'sdeath.Asthepressureoftheinvestigationintensifies,Lucinda'srelationshipwithhusbandTom,playedbyLorneMacFadyen(Pistol,Vigil)startstofracture,andherconfidentprofessionalexteriorbeginstocrack.IsLucindahidingsomething?Throughthecatandmousethrillerofthemedicalinvestigation,Malpracticetellsthestoryofadamageddoctorcaughtupinadangerousconspiracy.